AG Long-COVID & ME/CFS

Task-Evoked Pupillary Dynamics Are Altered in Post-COVID Syndrome

Smit, A., Fleischmann, P., Knauer, T. S., Mardin, C. Y., Michelson, G., Zott, J., Güttes, M., Sarmiento, H., Ilgner, M., Jakobi, M., Rech, J., & Hohberger, B. 

Medical Sciences, 2026 May 21;14(2):269. https://doi.org/10.3390/medsci14020269

https://pubmed.ncbi.nlm.nih.gov/42201061/

An Explorative Approach to Examining the Role of Ischemia and Inflammation on the Function of Autoantibodies Against G Protein–Coupled Receptors and Their Corresponding Agonists

Wallukat, G., Lakatos, P., Steinhorst, K., Flecks, M., & Hohberger, B. (2026). International 

Journal of Molecular Sciences, 2026 Mar 19;27(6):2797. https://doi.org/10.3390/ijms27062797

https://pubmed.ncbi.nlm.nih.gov/41898657/

3D Virtual Reality Performance Metrics as a Future Fatigue Biomarker in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

Ladek, A.-M., Priebe, L., Harrer, T., Harrer, E., Michelson, G., Knauer, T. S., Dias-Nunes, D. X., Mardin, C. Y., Bergua, A., & Hohberger, B. (2026).  

Biomedicines, 2026 Apr 9;14(4):855. https://doi.org/10.3390/biomedicines14040855

https://pubmed.ncbi.nlm.nih.gov/42072397/

Evaluation of Stereopsis Performance, Gaze Direction and Pupil Diameter in Post-COVID Syndrome Using Machine Learning

Knauer, T. S., Mardin, C. Y., Rech, J., Michelson, G., Stog, A., Zott, J., Steußloff, F., Güttes, M., Sarmiento, H., Ilgner, M., Jakobi, M., Hohberger, B., & Schottenhamml, J. 

Biomedicines, 2025 Nov 20;13(11):2828. https://doi.org/10.3390/biomedicines13112828

https://pubmed.ncbi.nlm.nih.gov/41301920/

Safety, tolerability and clinical effects of rovunaptabin, also known as BC007 on fatigue and quality of life in patients with Post-COVID syndrome (reCOVer): A prospective, exploratory, placebo-controlled, double-blind, randomised phase IIa clinical trial (RCT)

Hohberger, B., Ganslmayer, M., Harrer, T., Kruse, F., Maas, S., Borst, T., Heimke-Brinck, R., Stog, A., Knauer, T., Rühl, E., Zeisberg, V., Skornia, A., Bartsch, A., Ströbel, A., Wytopil, M., Merkel, C., Hofmann, S., Schmidt, K. G., Lakatos, P., Schottenhamml, J., Herrmann, M., Mardin, C., Rech, J. 

eClinicalMedicine, 2025 Jul 22:86:103358. https://doi.org/10.1016/j.eclinm.2025.103358

https://pubmed.ncbi.nlm.nih.gov/40735347/

Functional Autoantibodies Targeting G-Protein-Coupled Receptors and Their Clinical Phenotype in Patients with Long-COVID 

Hofmann, S., Lucio, M., Wallukat, G., Hoffmanns, J., Schröder, T., Raith, F., Szewczykowski, C., Skornia, A., Rech, J., Schottenhamml, J., Harrer, T., Ganslmayer, M., Mardin, C., Flecks, M., Lakatos, P., & Hohberger, B.

International Journal of Molecular Sciences, 2025 Jul 14;26(14):6746. https://doi.org/10.3390/ijms26146746

https://pubmed.ncbi.nlm.nih.gov/40724994/

Deoxygenation Trends and Their Multivariate Association with Self-Reported Fatigue in Post-COVID Syndrome

Ladek, A.-M., Lucio, M., Weiß, A., Knauer, T., Sarmiento, H., Ilgner, M., Jakobi, M., Barteczko, L., Ganslmayer, M., Rech, J., Bergua, A., Mardin, C. Y., & Hohberger, B. 

Biomedicines, 2025 Jun 3;13(6):1371. https://doi.org/10.3390/biomedicines13061371

https://pubmed.ncbi.nlm.nih.gov/40564090/

Long COVID: Association of Functional Autoantibodies against G-Protein-Coupled Receptors with an Impaired Retinal Microcirculation

Szewczykowski C, Mardin C, Lucio M, Wallukat G, Hoffmanns J, Schröder T, Raith F, Rogge L, Heltmann F, Moritz M, Beitlich L, Schottenhamml J, Herrmann M, Harrer T, Ganslmayer M, Kruse FE, Kräter M, Guck J, Lämmer R, Zenkel M, Gießl A, Hohberger B.

Int J Mol Sci. 2022 Jun 29;23(13):7209. doi: 10.3390/ijms23137209. PMID: 35806214; PMCID: PMC9266742.

Post-COVID-19 Syndrome: Retinal Microcirculation as a Potential Marker for Chronic Fatigue.

Schlick S, Lucio M, Wallukat G, Bartsch A, Skornia A, Hoffmanns J, Szewczykowski C, Schröder T, Raith F, Rogge L, Heltmann F, Moritz M, Beitlich L, Schottenhamml J, Herrmann M, Harrer T, Ganslmayer M, Kruse FE, Lämmer R, Mardin C, Hohberger B.

Int J Mol Sci. 2022 Nov 8;23(22):13683.

Case Report: Neutralization of Autoantibodies Targeting G-Protein-Coupled Receptors Improves Capillary Impairment and Fatigue Symptoms After COVID-19 Infection.

Hohberger B, Harrer T, Mardin C, Kruse F, Hoffmanns J, Rogge L, Heltmann F, Moritz M, Szewczykowski C, Schottenhamml J, Kräter M, Bergua A, Zenkel M, Gießl A, Schlötzer-Schrehardt U, Lämmer R, Herrmann M, Haberland A, Göttel P, Müller J, Wallukat G.

Front Med (Lausanne). 2021 Nov 18;8:754667.
doi: 10.3389/fmed.2021.754667. eCollection 2021. PMID: 34869451
https://pubmed.ncbi.nlm.nih.gov/34869451/

Retinal Microcirculation as a Correlate of a Systemic Capillary Impairment After Severe Acute Respiratory Syndrome Coronavirus 2 Infection

Bettina Hohberger, Marion Ganslmayer, Marianna Lucio, Friedrich Kruse, Jakob Hoffmanns, Michael Moritz, Lennart Rogge, Felix Heltmann, Charlotte Szewczykowski, Julia Fürst, Maximilian Raftis, Antonio Bergua, Matthias Zenkel, Andreas Gießl, Ursula Schlötzer-Schrehardt, Paul Lehmann, Richard Strauß, Christian Mardin, Martin Herrmann

Front Med (Lausanne). 2021 Jul 9;8:676554. doi: 10.3389/fmed.2021.676554. eCollection 2021.
PMID: 34307408 PMCID: PMC8299003 DOI: 10.3389/fmed.2021.676554
https://pubmed.ncbi.nlm.nih.gov/34307408/

Agonistic autoantibodies against ß2-adrenergic receptor influence retinal microcirculation in glaucoma suspects and patients.

Hohberger B, Hosari S, Wallukat G, Kunze R, Krebs J, Müller M, Hennig T, Lämmer R, Horn F, Muñoz LE, Herrmann M, Mardin C.

PLoS One. 2021 May 7;16(5):e0249202.
doi: 10.1371/journal.pone.0249202. eCollection 2021. PMID: 33961631
https://pubmed.ncbi.nlm.nih.gov/33961631/

Physical phenotype of blood cells is altered in COVID-19

Markéta Kubánková, Bettina Hohberger, Jakob Hoffmanns, Julia Fürst, Martin Herrmann, Jochen Guck, Martin Kräter

Biophys J. 2021 Jul 20;120(14):2838-2847. doi: 10.1016/j.bpj.2021.05.025. Epub 2021 Jun 2.
PMID: 34087216 PMCID: PMC8169220 DOI: 10.1016/j.bpj.2021.05.025
https://pubmed.ncbi.nlm.nih.gov/34087216/

OCT Angiography as an Interdisciplinary Diagnostic Tool for Systemic Diseases

Bettina Hohberger, Christian Y. Mardin

Klin Monbl Augenheilkd. 2021 Dec;238(12):1294-1298. doi: 10.1055/a-1654-0504.
PMID: 34879428 DOI: 10.1055/a-1654-0504

Abstract: In recent years, OCT angiography (OCT-A) has emerged as a well established imaging modality of the retina. This allows non-invasive visualisation of the retinal circulation at a micrometre scale in eye disorders and systemic diseases with potential ocular involvement. This review summarises the current state of this topic.

https://pubmed.ncbi.nlm.nih.gov/34879428/

Functional autoantibodies against G-protein coupled receptors in patients with persistent Long-COVID-19 symptoms

Gerd Wallukat, Bettina Hohberger, Katrin Wenzel, Julia Fürst, Sarah Schulze-Rothe, Anne Wallukat, Anne-Sophie Hönicke, Johannes Müller

J Transl Autoimmun. 2021;4:100100. doi: 10.1016/j.jtauto.2021.100100. Epub 2021 Apr 16.
PMID: 33880442 PMCID: PMC8049853 DOI: 10.1016/j.jtauto.2021.100100

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Wenn Sie gezielt einen bestimmten Forschungsbereich unterstützen möchten, geben Sie im Verwendungszweck hinter “AG Hohberger” noch eines der jeweiligen Schlagworte an:

• Long COVID
• ME/CFS
• Post Vac
• Glaukom
• Autoimmunerkrankungen

Wir danken Ihnen vielmals für Ihre Unterstützung!

Universitätsklinikum Erlangen
Augenklinik
Schwabachanlage 6
91054 Erlangen

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